三种引产方式在中晚期妊娠引产中的应用价值体现

[摘要] 目的 分析不同引产方式在中晚期妊娠引产中的应用效果。

方法 选择2011年1月~2012年12月本院妇产科收治的160例孕13~36周自愿终止妊娠的孕妇作为研究对象,根据孕周分为中期妊娠组(孕13~27周)85例、晚期妊娠组(28~36周)75例,两组患者中根据孕妇自身情况分别选择利凡诺羊膜腔内注射引产(A组)、水囊+缩宫素静脉滴注引产(B组)、米非司酮配合利凡诺羊膜腔内注射引产(C组)。

比较[毕业论文 网专业提供代写医学论文的服务,欢迎光临中晚期妊娠组中孕妇不同种引产方式的引产效果。

结果 85例中期妊娠者中,C组的宫缩开始时间、产程时间、住院时间明显短于A、B组,住院费用明显低于A、B组,产后出血量明显少于A、B组,差异有统计学意义(P0.05);75例晚期妊娠者中,B组的宫缩开始时间、产程时间、住院时间明显短于A、C组,住院费用明显低于A、C组,产后出血量明显少于A、C组,差异有统计学意义(P0.05)。

结论 中期妊娠者宜选择米非司酮配合利凡诺羊膜腔内注射引产方式,而晚期妊娠者宜选择水囊+缩宫素静脉滴注引产方式,以期达到最佳引产效果。

[关键词] 引产方式;中晚期妊娠;应用效果   [中图分类号] R719.3 [文献标识码] A [文章编号] 1674—4721(2014)11(c)—0020—03   [Abstract] Objective To analyze the application effect of different abortion methods in induced labour mode in the induced labour during middle and late pregnancy. Methods 160 pregnant women with voluntary termination of pregnancy at 13—36 weeks of gestation treated in our hospital from January 2011 to December 2012 were selected as the study objectives. According to gestational age,the pregnant women were divided into the mid—pregnancy group (13—27 weeks gestation,n=85) and the late pregnancy group (28—36 weeks,n=75),patients in the two groups were given the abortion rivanol amniotic injection (the group A),the water sac+oxytocin for intravenous induction (the group B),mifepristone combined with rivanol intra amniotic injection induction (the group C),the induced labour effect of different induced labour mode in the middle and late pregnancy group. Results 85 cases in the mid—pregnancy group,contractions start time,labor time,hospitalization time in the group C was significantly shorter than that in the group A and B,hospitalization cost in the group C was significantly lower than that in the group A and B,the amount of postpartum hemorrhage in the group C was significantly was fewer than that in the group A and B,and there was a statistical difference (P0.05).75 cases in the late pregnancy,labor time,hospitalization time in the group B was significantly shorter than that in the group A and C,hospitalization cost in the group B was significantly lower than that in the group A and C,the amount of postpartum hemorrhage in the group B was significantly was fewer than that in the group A and C,and there was a statistical difference (P0.05). Conclusion Mifepristone combined with rivanol intra amniotic injection induction is selected by the pregnant women in middle pregnancy,while the water sac+oxytocin for intravenous induction in late pregnancy in order to achieve optimal induced labour effect.  [Key words] Induced labour mode;Middle and late pregnancy;Application effect   中晚期引产的概念是指在妊娠中晚期(13孕周),用人工的方法诱发宫缩,排出妊娠物的过程[1]。

中晚期妊娠引产对产妇的身体、心理均造成较大伤害。

目前中晚期引产方式有多种:利凡诺羊膜腔穿刺引产、米非司酮配伍米索前列醇引产水囊引产缩宫素引产以及在此类基础上相互组合形成的诸多引产方式[2]。

本研究重点探讨中晚期妊娠者采用不同引产方式的效果,现报道如下。

1 资料与方法   1.1 一般资料   选择2011年1月~2012年12月本院妇产科收治的160例孕13~36周自愿终止妊娠的孕妇作为研究对象,均无烟酒嗜好,无长期服药史,近3个月未用甾体类药物,无米非司酮禁忌证,B超检查为单胎妊娠,且符合停经月份,无上述药物使用禁忌。

年龄25~38岁,平均(27.81.2)岁。

根据孕周分为中期妊娠组(孕13~27周)85例、晚期妊娠组(28~36周)75例,两组患者根据引产方式进一步细分为A组(利凡诺羊膜腔内注射引产)、B组(水囊+缩宫静脉滴注引产)、C组(米非司酮配合利凡诺羊膜腔内注射引产),3组患者的基本资料差异无统计学意义(P0.05),具有可比性。

1.2 引产方法   ①利凡诺羊膜腔内注射引产:在引产当天对患者羊膜腔内注射100 mg利凡诺;②水囊联合缩宫素静脉滴注引产:取膀胱截石位,常规消毒、铺巾,将外阴扩开以使宫颈充分暴露,对宫颈前唇进行有效固定,碘伏消毒阴道,在宫颈管内放入无菌水囊,向水囊内注入300 ml生理盐水[3]。

放置水囊后12 h 给予缩宫素注射液,生理盐水注射液500 ml+ 2.5 U缩宫素注射静脉滴注[4];③引产当天一次空腹服用米非司酮150 mg 2 h后,行羊膜腔内注射利凡诺100 mg[5]。

观察所有孕妇的宫缩开始时间,产程时间,胎盘滞留、粘连情况,产后出血量,清宫率,总住院时间,住院费用等指标。

1.3 统计学处理   数据采用SPSS 17.0软件进行统计分析,计量资料以均数标准差(xs)表示,采用t检验,计数资料采用2检验,以P0.05为差异有统计学意义。

2 结果   2.1 中期妊娠组中3组相关观察指标的比较   85例中期妊娠者中,C组的宫缩开始时间、产程时间、住院时间明显短于A、B组,住院费用明显低于A、B组,产后出血量明显少于A、B组,差异有统计学意义(P0.05)(表1)。

2.2 晚期妊娠组中3组相关观察指标的比较   75例晚期妊娠者中,

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