布地奈德雾化吸入治疗毛细支气管炎疗效分析

[摘要] 目的 探讨布地奈德雾化吸入治疗毛细支气管炎的临床疗效。

方法 随机选取2015年1月―2016年1月江苏省沛县人民医院儿科毛细支气管炎住院患儿60例,随机分成两组对照组30例给予常规治疗治疗组30例在常规治疗的基础上加用吸入布地奈德混悬液雾化吸入,观察两组患儿主要临床症状、体征消失时间及住院天数。

结果 治疗组与对照组的憋喘时间分别为(5.0±0.5)d与(6.2±0.4)d;肺部哮鸣音消失时间分别为(5.8±0.3)d与(6.8±0.2)d;住院天数分别为(7.0±0.4)d与(7.9±0.6)d,两组差异均有统计学意义(P毕业论文网   [关键词] 布地奈德雾化吸入毛细支气管炎   [中图分类号] R725 [文献标识码] A [文章编号] 1674—0742(2016)09(a)—0117—03   [Abstract] Objective To observe the clinical efficacy of nebulized budesonide inhalation in treatment of bronchiolitis. Methods Random selection January 2015 ― January 2016 Pei County, Jiangsu Province People‘s Hospital pediatric bronchiolitis hospitalized children 60 cases were randomly divided into two groups, the control group (30 cases) given conventional treatment, treatment group (30 cases) on the basis of conventional treatment combined with inhalation with budesonide suspension liquid atomization inhalation, observe two groups of children with main clinical symptoms and signs disappeared time and length of hospital stay. Results In the treatment group and control group in the breath holding time was (5.0±0.5)d and (6.2±0.4)d; wheezing stridor disappeared time (5.8±0.3)d and (6.8±0.2)d, respectively; and length of stay were(7.0±0.4)d and (7.9±0.6)d, the difference between the two groups were statistically significant (P   两组患儿治疗后均取得较好疗效,但在缓解憋喘症状、促进肺部哮鸣音消失,减少住院天数方面治疗组明显优于对照组两组间差异有统计学意义(P参考文献]   [1] 刘恩梅,陈慧中.努力提高中国儿科医生规范诊治毛细支气管炎的水平[J].中华儿科杂志,2015,53(3):161—163   [2] 中华医学会儿科学分会呼吸学组毛细支气管炎诊断、治疗与预防专家共识:2014年版[J].中华儿科杂志,2015,53(3):168—170   [3] 王卫平.儿科学[M].8版.北京:人民卫生出版社,2013:269—271   [4] 高萌,吴福玲.毛细支气管炎与间充质干细胞的相关性研究[J] . 国际儿科学杂志, 2015,42(2):135—170   [5] 申昆玲,邓力,李云珠,等.糖皮质激素雾化吸入疗法在儿科应用的专家共识:2014年修订版[J].临床儿科杂志, 2014,32(6):504—511,   [6] 赵荧,李玉梅,安彩侠,等.布地奈德对哮喘大鼠气道重塑及支气管肺泡灌洗液、肺组织中转化生长因子—β1表达的影响[J] . 临床儿科杂志 2010,28(2):173—177   [7] 蔡栩栩.关于“高剂量吸入性糖皮质激素是否可以产生快速效应”的答复[J].中国小儿急救医学2016,23(4):280~281   [8] 王浩,尚云晓.吸入高渗盐水及肾上腺素对治疗急性中重度毛细支气管炎患儿疗效的研究[J].中国小儿急救医学2015,22(1):22—26   (收稿日期:2016—06—07)。

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