右美托嘧啶用于神经外科术后患者辅助镇痛的临床分析

[摘要] 目的 分析右美托嘧啶用于神经外科术后患者辅助镇痛的临床效果。

方法 随机选取2014年4月―2015年5月该院收治的80例行神经外科术后的患者随机分为观察组和对照组，给予观察组常规西药联合右美托嘧啶进行镇痛治疗，给予对照组常规西药进行镇痛治疗，对比两组术后不同时间点的VAS 评分和Ramsay评分。

结果 术后在6 h、12 h和24 h时间点内，观察组的VAS 评分均低于对照组，Ramsay评分均高于对照组，且差异均较大，P毕业论文网 　　[关键词] 右美托嘧啶；神经外科术；镇痛；躁动 　　[中图分类号] R5 [文献标识码] A [文章编号] 1674—0742（2016）01（b）—0165—02 　　Clinical Analysis of Dexmedetomidine in the Supplementary Analgesic Treatment of Patients after Neurosurgical Operation 　　LI Ping 　　Department of Anesthesiology， Shandong Medical University Hospital， Zibo， Shandong Province， 255400 China 　　[Abstract] Objective To analyze the clinical effect of Dexmedetomidine in the supplementary analgesic treatment of patients after neurosurgical operation. Methods 80 cases of patients after neurosurgical operation treated in our hospital from April 2014 to May 2015 were selected and randomly divided into two groups， the observation group were treated with routine western medicine combined with Dexmedetomidine for analgesic treatment， the control group were treated with routine western medicine for analgesic treatment， the VAS score and Ramsay score of the two groups at different time points were compared. Results At 6h，12h and 24h after operation， the VAS score in the observation group was lower than that in the control group， the Ramsay score was higher than that in the control group， and the differences were big P统计学比较，两组患者在性别、年龄、手术原因及麻醉方法方面比较差异无统计学意义（P>0.05），具有可比性。

1.2 术后镇痛方法 　　给予对照组常规西药镇痛治疗，具体如：将100 ug舒芬太尼、5 mg 托烷司琼加入100 mL生理盐水中，通过镇痛泵进行镇痛治疗，控制输注速度为 2 mL/h。

给予观察组常规西药+右美托嘧啶镇痛治疗，具体如：将 1～2 ug/kg右美托嘧啶、100 ug舒芬太尼、5 mg 托烷司琼加入100 mL生理盐水中，通过镇痛泵进行镇痛治疗，控制输注速度为 2 mL/h。

1.3 观察指标 　　观察两组术后不同时间点的视觉模拟评分法（VAS 评分）和镇静评分（Ramsay评分），包括6 h、12 h及24 h，并进行对比。