不同剂量地佐辛辅助罗哌卡因用于术后患者硬膜外自控镇痛的临床探

[摘要] 目的 探讨不同剂量地佐辛静点辅助罗哌卡因用于术后患者硬膜外自控镇痛的镇痛效果和副作用的差异。

方法 随机选择2014年5月―2015年4月该院收治的90例择期妇科下腹部开腹手术患者，随机分为3组， 每组30例，Ⅰ组地佐辛0.0075 mg?（kg?h）—1， Ⅱ组地佐辛0.0075 mg?（kg?h）—1辅助 0.2%甲磺酸罗哌卡因硬膜外镇痛，Ⅲ组地佐辛0.01 mg?（kg?h）—1辅助 0.2%甲磺酸罗哌卡因硬膜外镇痛，3组地佐辛均为静点，Ⅱ组、Ⅲ组术毕硬膜外腔给予0.2%甲磺酸罗哌卡因负荷量后接镇痛泵，观察术后2、6、12、24、36、48 h的ECG、SPO2、RR、BP疼痛及镇静评分并记录恶心呕吐瘙痒等不良反应。

结果 3组患者镇静评分差异无统计学意义，疼痛评分（VAS）Ⅱ组和Ⅲ组均显著低于Ⅰ组，差异有统计学意义?vP毕业论文网 /6/view—11627109.htm　　[关键词] 硬膜外自控镇痛；地佐辛；镇痛效果 　　[中图分类号] R614 [文献标识码] A [文章编号] 1674—0742（2015）08（c）—0121—03 　　Different Doses of Dezocine Assist Patients with Clinical Observation of Ropivacaine for Patient—controlled Epidural Analgesia after Operation 　　QIN Shu—guo， ZHOU Ying， ZHAO Ming， CHEN Wen—li， ZHANG Le 　　Department of Anesthesiology， Inner Mongolia Autonomous Region Corps Hospital of Chinese People‘s Armed Police Force， Hohhot， Inner Mongolia Autonomous Region， 010040 China 　　[Abstract] Objective To observe different doses of dezocine intravenous assisted ropivacaine for analgesia in patients between epidural analgesia and postoperative side effects. Methods In 2014 May —2015 year in April 90 cgynecological abdominal operation were randomly divided into three groups， 30 cases in each group， one group of dezocine 0.0075 mg?（kg?h）—1 II group， dezocine 0.0075 mg?（kg?h）—1 0.2% ropivacaine for epidural analgesia group， dezocine 0.01 mg?（kg?h）—1 0.2% a Ropivacaine Mesylate epidural analgesia， 3 groups were intravenous dezocine， group II， group III postoperative epidural 0.2% Ropivacaine Mesylate load after analgesia pump， observed after 2， 6， 12， 24， 36， 48 h， ECG， SPO2， RR， BP pain and sedation scores and record the adverse reaction of nausea and vomiting. Results Three patients with no significant sedation score， pain score（VAS） in group II and III group were significantly lower than those of group I， was statistically significant （P。