青年人结肠癌76例临床分析
【关键词】 ,,结肠癌。
(广东省普宁市华侨医院， 广东 普宁 515300）。
摘 要：目的：探讨青年人结肠癌的临床病理特点。方法：收集1996年1月至2003年12月，7年间经纤维结肠镜（或手术）病理确诊的结肠癌病例，并就发现76例青年人结肠癌发病情况及相关资料进行分析，将所有病例按年龄划分为青年组（年龄40岁）和中老年组（年龄40岁）。结果：青年人结肠癌发病率男性高于女性，组织病理学类型以低分化腺癌（42.11%）、粘液细胞癌（19.74%）为多，病程≤9个月者占（51.32%）。结论：临床病程短，病理组织学分化差是青年人结肠癌预后差的重要原因。提高对青年人结肠癌的认识，做到早期诊断，早期治疗，是改善预后的关键。
Clinical Analysis of 76 Cases Colon Carcinoma in Youth。
Abstract: Objective: To investigate the clinical and pathological characteristics of colon carcinoma in youth. Methods: Collected all cases of colon carcinoma admited from January 1996 to December 2003, and divided all these cases into youth group (40 yrs) and middle—aged and older—aged group (40 yrs). The incidence and other correlated data of 76 cases of colon carcinoma in youth were studied. Results：The incidence of colon carcinoma in youth was higher in male than in female, and the poorly differentiated adenocarcinoma（42.11%）and Krukenberg tumor （19.74%） were more common in histopathology. The course of disease less than 9 months were found in 51.32% of cases. Conclusion: Shorter course of disease and poorly differentiated in histopathology were the important reasons of bad prognosis in colon carcinoma in youth. To enhanced the recognition of colon carcinoma in youth and to diagnose and treat in early may be the key point for improving the prognosis.
Key words: Colon carcinoma; Pathology; Prognosis。
本文对我院经结肠镜（或手术）病理确诊的76例青年（20～39岁）结肠癌进行回顾分析如下：
1 资料与方法。
收集自1996年1月至2003年12月我院经结肠镜（或手术）病理确诊的结肠癌683例，将全部病例按年龄分为两组，即青年组（20～39岁），中老年组（40岁），发现青年人结肠癌病例76例，中老年人结肠癌607例，并就青年人结肠癌的临床，病理特征与中老年组做相应对照，结果用x2检验。
2 结 果。
2.1 发病情况，76例青年人结肠癌中，男42例，女34例，男女之比1:0.81，年龄20～39岁，平均年龄28.41岁。占同期结肠癌检出率的12%，中老年人结肠癌607例，男344例，女263例，男女之比1:0.76，平均年龄60.42岁。
2.2 临床症状与诊断：76例青年人结肠癌中，腹痛57例，（75.00%）粘液血便36例（47.38%），纳差消瘦49例（64.47%）腹部包块18例（23.68%），贫血27例（35.53%），腹水7例（9.34%）,腹部胀满31例(40.79%)，青年人结肠癌的主要诊断方法是结肠纤维镜，病理活检。